Regional Difference of Genetic Polymorphism in Korea for Determination of Subpopulation.

Lee, Soong Deok; Lee, Jung Bin; Lee, Yoon Seong

Original article

Korean Journal of Legal Medicine 1998;22(1):19-26.
Published online May 31, 1998.

Regional Difference of Genetic Polymorphism in Korea for Determination of Subpopulation.

Soong Deok Lee, Jung Bin Lee, Yoon Seong Lee

Department of Forensic Medicine, Seoul National University, College of Medicine, Korea.

Abstract

To confirm whether there exist the subpopulation in Korea, the genetic profiles for the residents in three representative regions, Cheju-island, Cheonla-do, Gyeongsang-do were compared. VNTR D1S80 loci, STR vwF loci and MBP loci were studied, and distribution and frequency of each allele, observed and expected heterozygosity, observed number of alleles and genotypes were compared for the above three and artificially amalgamated group. The number of alleles was smaller in some loci, but this was thought to be due to the different sample number. The difference between observed and expected heterozygosity was also insignificant. From these it seemed that the subpopulation did not exist in Korea.