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Korean Journal of Legal Medicine 2008;32(1):68-71.
Published online May 31, 2008.
Change of Surname?: An application of Y-STR Haplotyping.
Ki Min Seong, Seong Yeon Yoo, Jung Ho Hwang, Nam Soo Cho, Seong Ho Kim, Young Shik Choi
Department of Forensic Medicine, Central District Office, NISI, Daejeon 305-348, Korea. cns6999@nisi.go.kr
Abstract
Y-STR haplotyping is a powerful forensic and anthropological tool for identifying male lineages. We used high-resolution Y-STR haplotyping to evaluate the possibility of an ancestral relationship between two individuals with the different surname. Of the 17 Y-STRs genotyped, 16 had identical alleles in two individuals, except for an unambiguously sporadic mutation (one-step mutation) at DYS385 locus. The common allele 11.1 (U3Ains) at DYS439 locus was also observed in these two individuals. Sequencing analysis of these alleles of two samples demonstrated an A insertion at base 3 upstream from the repeat region's first GATA motif. These findings suggested that two individuals were paternally related, even if male individuals live with different surname.
Key Words: Y-STR, surname, haplotypes, mutation


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