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Korean J Leg Med > Volume 44(1); 2020 > Article
Korean Journal of Legal Medicine 2020;44(1):37-40.
DOI: https://doi.org/10.7580/kjlm.2020.44.1.37    Published online February 29, 2020.
Lung Pathology in Septic Shock with Leukopenia.
Gi Yeong Huh
1Department of Forensic Medicine, Pusan National University School of Medicine, Yangsan, Korea. gyhuh@pusan.ac.kr
2Department of Pathology, Pusan National University Hospital, Busan, Korea.
Abstract
Sepsis-related deaths are occasionally encountered in forensic practice. However, forensic pathologists are reluctant to use the terminology “sepsis” or “septic shock” as a cause of death because of the lack of definite morphological evidence. When sepsis is considered a cause of death, pathologic assessment is essential to identify the foci of infection or consequences of sepsis, such as diffuse alveolar damage (DAD). Pneumonia is known to be a common source of sepsis and can develop into DAD with progression of sepsis. The histology of DAD varies according to the immunologic status. An autopsy of a 55-year-old man who died of septic shock with leukopenia revealed only abundant gram-negative bacilli in the alveoli without typical DAD pathology.
Key Words: Septic shock, Leukopenia, Lung, Pathology, Diffuse alveolar damage
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