A Study on Secretor Status of Cl Blood Type in Human Saliva

, Sun Weon Park

Original Article

Korean Journal of Legal Medicine 1988;12(1):22-25.

Department of Legal Medicine, Korea University, College of Medicine, Seoul, Korea

Abstract

Moon and Wiener had demonstrated new blood factor "Cl" with anti-Cl lectin prepared from extracts of seeds of Korean Clerodendron trichotomum THUNBERG by absorption of selected human red blood cells. After that, Moon et al. had reported that Cl type specific substance is distributed in human saliva, too. Therefore, human saliva can be classified into two types, secretor of Cl (Sc) and non-secretor of Cl (nSc). To study on the frequency of Sc and nSc, relation with ABH type secretor and hereditary pattern of CI secretors, agglutination inhibition test of anti-CI lectin was carried out with human saliva by standard method, and the results can be summarized as follows: 1. Cl positive type can be classified secretor and non-secretor of Cl by human saliva, but Cl negative type is reacted as only non-sectetor of Cl. 2. The secretor status of Cl is quite different from ABH secretor. 3. It appears that the inheritance of the saliva type of Cl follows the Mendelism law with the non-secretor of Cl transmitted through recessive genes.